関連する実験動画

Updated: Feb 5, 2026

CRISPR Guide RNA Cloning for Mammalian Systems
06:48

CRISPR Guide RNA Cloning for Mammalian Systems

Published on: October 2, 2018

73.0K

CRISPR-Cas13dのRNA誘導リボヌクレアース活性に対する構造的基礎

Cheng Zhang1, Silvana Konermann2, Nicholas J Brideau2

  • 1Laboratory of Genetics, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA; Helmsley Center for Genomic Medicine, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|September 23, 2018
PubMed
まとめ

研究者は,CRISPR-Casシステムの重要な構成要素であるコンパクトなCas13d酵素の構造と機能を明らかにしました. これは,高度なトランスクリプトーム工学のためのRNA誘導RNAターゲティングの洞察を提供します.

キーワード:
CRISPRについてカス13カス13dカス9RNA 干渉RNAターゲティングクリオ・エムshRNA について構造タイプVI

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