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Updated: Feb 4, 2026

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
09:32

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis

Published on: October 15, 2021

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MHCクラスII結合がん変異に対する進化的圧力

Rachel Marty Pyke1, Wesley Kurt Thompson2, Rany M Salem3

  • 1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA.

Cell
|September 25, 2018
PubMed
まとめ

CD4+ T細胞は,腫瘍の進化に影響を与えることで,抗腫瘍免疫において重要な役割を果たします. MHC- IIのプレゼンテーションは癌の変異を抑制し,腫瘍の発達に影響を与え,CD4+T細胞の反応の重要性を強調します.

キーワード:
MHC-II についてT細胞癌についてドライバー変異免疫編集免責権免疫療法腫瘍の進化

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