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Updated: Feb 4, 2026

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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GPCRの自然変異と人工変異は,C. elegansのDEET耐性を促進する

Emily J Dennis1, May Dobosiewicz2, Xin Jin2,3

  • 1Laboratory of Neurogenetics and Behaviour, The Rockefeller University, New York, NY, USA.

Nature
|September 28, 2018
PubMed
まとめ

N,N-ダイエチルメタトルーアミド (DEET) は 嗅覚経路を乱すことで 昆虫やネマトードの行動を乱します 研究者は,特定の遺伝子であるstr-217と,DEETに不可欠なC. elegansのADLニューロンを特定しました.

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