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Updated: Feb 4, 2026

Evaluation of Caspase Activation to Assess Innate Immune Cell Death
10:23

Evaluation of Caspase Activation to Assess Innate Immune Cell Death

Published on: January 20, 2023

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NONOは核HIVカプシドを検出し,cGAS媒介による先天性免疫活性化を促す

Xavier Lahaye1, Matteo Gentili1, Aymeric Silvin1

  • 1Immunity and Cancer Department, Institut Curie, PSL Research University, INSERM U932, 75005 Paris, France.

Cell
|October 2, 2018
PubMed
まとめ

タンパク質NONOは,核内のHIVカプシドの重要なセンサーとして作用し,ウイルスに対するサイクルGMP- AMP合成酵素 (cGAS) 免疫応答を活性化するために不可欠です.

キーワード:
HIV-1 ウイルスHIV-2 ウイルスノノ ノノスティングcGAS についてカプシドデンドリット細胞生まれながらの免疫センサー生まれつきの免疫マクロファージ

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