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Updated: Feb 4, 2026

Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
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低ナノモラーO-GlcNAc移転酵素阻害剤の構造に基づく進化

Sara E S Martin1, Zhi-Wei Tan1, Harri M Itkonen1

  • 1Department of Microbiology , Harvard Medical School , Boston , Massachusetts 02115 , United States.

Journal of the American Chemical Society
|October 5, 2018
PubMed
まとめ

研究者は,O-リンクされたN-アセチルグルコサミントランスファーゼ (OGT) の強力な細胞透過性阻害剤を開発した. これらの新しい化合物は,OGTをターゲットにしています.

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