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Updated: Feb 4, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages

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マクロファージの先天的反応を活性化するには,リン酸化媒介によるIFN-γR2膜転位が必要である

Xiaoqing Xu1, Jia Xu2, Jiacheng Wu2

  • 1Department of Immunology and Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, 100005 Beijing, China; National Key Laboratory of Medical Immunology and Institute of Immunology, Second Military Medical University, 200433 Shanghai, China.

Cell
|October 16, 2018
PubMed
まとめ

E- セレクチンは,インターフェロン- ガンマ受容体2 (IFN- γR2) の膜転位を活性化して,先天的な免疫反応を強化することで,リステリア感染中のマクロファージの活性化に不可欠です.

キーワード:
BTK についてEセレクチンEFhd2 についてIFN-γR2生まれつきの免疫マクロファージリン酸化

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