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Sampling Plans01:23

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The planning phase of the nursing process helps nurses set priorities, outline patient-centered goals and expected outcomes, and tailor nursing interventions to align with the aligned care plan. Through the planning phase, the nurse applies critical thinking skills to align and develop interventions according to the patient's needs. It provides continuity of care allowing patients to receive the maximum benefit from treatment. It serves as a pilot plan for allocating individual staff to a...
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運動計画のための皮質-小脳ループ

Zhenyu Gao1, Courtney Davis2, Alyse M Thomas2

  • 1Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands.

Nature
|October 19, 2018
PubMed
まとめ

小脳は運動計画中に 前頭皮質の活動を維持するために不可欠です この研究は 単純な運動制御を超えた 認知プロセスに不可欠な 皮質-小脳回路を明らかにしています

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科学分野:

  • 神経科学
  • 認知神経科学
  • モーター コントロール

背景:

  • 前頭皮質の持続的な神経活動が 運動に先立ちますが その脳の領域と相互作用は 完全に理解されていません
  • 伝統的に運動制御と結びついている小脳は 計画と記憶を含む 認知機能における役割がますます認識されています

研究 の 目的:

  • 運動計画中に前頭皮質の準備活動の維持における小脳の役割を調査する.
  • 運動計画における認知過程の基礎にある神経回路と多領域の相互作用を解明する.

主な方法:

  • マウスは 方向性のある動きを計画するために 短期記憶を必要とする 感覚的差別の作業を行いました
  • 中央深層小脳核 (fastigial nucleus) と前頭皮質の静音化は採用された.
  • 前頭皮質と小脳核の神経活動が運動開始前に記録された.

主要な成果:

  • 動作の実行に影響を及ぼさず,作業のパフォーマンスを損なう.
  • 前頭皮質と小脳核は 動き直す数秒前に 準備活動を示した
  • 前頭皮質の静音化は小脳準備活動を取り除き,皮質準備活動を維持するには,小脳準備活動が必要であった.
  • 前頭皮質にタラマス経由で投射され,皮質-小脳ループを形成する.

結論:

  • 小脳は運動計画中に前頭皮質で持続的な神経表現を維持するために不可欠です.
  • コルティコ・セレベラーループは,ファスティジア核,タラムス,前頭皮質を巻き込み,運動計画の認知的側面をサポートします.
  • 脳の機能は オンラインの運動制御を超えて 計画や記憶の維持のような 認知プロセスを含みます