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Updated: Feb 3, 2026

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay
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コレステロールと膜タンパク質の結合を決定する コレステロール13C イーストとダイナミックな核極化NMRのラベル付け

Matthew R Elkins1, Ivan V Sergeyev2, Mei Hong1

  • 1Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.

Journal of the American Chemical Society
|October 20, 2018
PubMed
まとめ

この研究では,膜タンパク質のコレステロール結合部位を特定するための新しいNMRスペクトロスコーピーの方法が導入されています. この技術は,コレステロールとインフルエンザM2タンパク質の相互作用を成功裏にマッピングし,ウイルスの芽生えの重要な詳細を明らかにしました.

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