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Updated: Feb 3, 2026

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
09:37

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

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タンパク質集積物の構造指紋は,自然同位体豊富度におけるダイナミック核偏振強化固体NMRによるものである

Adam N Smith1, Katharina Märker1, Talia Piretra2

  • 1Univ. Grenoble Alpes , CEA, CNRS, INAC, MEM, F-38000 Grenoble , France.

Journal of the American Chemical Society
|October 20, 2018
PubMed
まとめ

ハンチントン病 (HD) のタンパク質集積は,同位体ラベルを付けずに固体NMR (ssNMR) を使用して構造的に指紋が取れます. この突破は,標識されていないタンパク質繊維の分析を可能にし,構造研究のための新しい長距離制約を提供します.

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