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Updated: Feb 3, 2026

Introducing Point Mutations into Human Pluripotent Stem Cells Using Seamless Genome Editing
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Introducing Point Mutations into Human Pluripotent Stem Cells Using Seamless Genome Editing

Published on: May 10, 2020

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幹細胞 と ゲノム 編集 と 翻訳 医学 の 道

Frank Soldner1, Rudolf Jaenisch2

  • 1The Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.

Cell
|October 20, 2018
PubMed
まとめ

胚性幹細胞 (ESC) と誘発性多能幹細胞 (iPSC) を含むヒト多能幹細胞は,中枢神経系疾患の研究と再生医療に革命的な可能性を秘めています. 幹細胞技術の進歩と ゲノム工学の組み合わせは 複雑な神経疾患の治療に 新しい道を開きます

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Consider the two thermodynamic processes involving an ideal gas that are represented by paths AC and ABC in Figure 1:
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