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Updated: Feb 3, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
08:05

Assaying Protein Kinase Activity with Radiolabeled ATP

Published on: May 26, 2017

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ATPを反転させ,キナーゼ機能を強化する

Joshua B Sheetz1, Mark A Lemmon1

  • 1Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA; Cancer Biology Institute, Yale University, West Haven, CT 06516, USA.

Cell
|October 20, 2018
PubMed
まとめ

細胞シグナル伝達において重要な触媒残基を欠くタンパク質キナーゼは困難である. ある研究で,ある擬似キナーゼがアデノシン・モノフォスファート (AMP) を基板に転送し,キナーゼ折りの新しい触媒的機能を示していることが明らかになった.

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