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Updated: Feb 3, 2026

Generation and Purification of Human INO80 Chromatin Remodeling Complexes and Subcomplexes
08:44

Generation and Purification of Human INO80 Chromatin Remodeling Complexes and Subcomplexes

Published on: October 23, 2014

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SWI/SNFファミリーのクロマチンの改造複合体のモジュール式組織と組み立て

Nazar Mashtalir1, Andrew R D'Avino1, Brittany C Michel2

  • 1Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Cell
|October 23, 2018
PubMed
まとめ

哺乳類のSWI/SNF (mSWI/SNF) 複合体は,ゲノム調節に不可欠であり,疾患に関与しています. この研究により,モジュール型の組織と組み立ての経路が明らかになり,将来の構造的および機能的研究に役立ちます.

キーワード:
ATP依存クロマチンの改造BAF複合体PBAF複合体SWI/SNF複合体について癌についてクロスリンク マススペクトロメトリー変異ncBAF複合体についてタンパク質複合体の組成サブユニット組織

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Biochemical Assays for Analyzing Activities of ATP-dependent Chromatin Remodeling Enzymes10:14

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