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Updated: Feb 3, 2026

SILAC Based Proteomic Characterization of Exosomes from HIV-1 Infected Cells
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ボロン酸によるHIV-1プロテアスのサブピコモラ抑制

Ian W Windsor1, Michael J Palte, John C Lukesh

  • 1Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.

Journal of the American Chemical Society
|October 23, 2018
PubMed
まとめ

ボロン酸は強い水素結合を形成し,新しいHIV-1プロテアース阻害剤を生成します. この新しい阻害剤は 薬剤耐性HIV変種に対してさえ 20倍以上の親和性を示しています

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