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Updated: Feb 3, 2026

Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis
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Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis

Published on: July 26, 2018

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形状的に不活性化されたリボヌクレオチド還元酵素の光化学的救済

Brandon L Greene1, JoAnne Stubbe, Daniel G Nocera1

  • 1Department of Chemistry and Chemical Biology , Harvard University , Cambridge , Massachusetts 02138 , United States.

Journal of the American Chemical Society
|October 23, 2018
PubMed
まとめ

クラスIアリボヌクレオチド還元酵素 (RNR) の活性性は,サブユニット間のラジカル転送 (RT) に依存しています. 特定の変異 (E350X) はこれをブロックしますが,光化学的救済はE350を明らかにします.

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