臨床実務における完全自動エコー・カルディオグラム解釈
Jeffrey Zhang1,2, Sravani Gajjala3, Pulkit Agrawal2
1Cardiovascular Research Institute (J.Z., R.C.D.).
Circulation
|October 26, 2018
まとめ
AIを用いた自動心臓画像分析は,エコーカルジオグラムを正確に解釈し,スケーラブルな患者のモニタリングと疾患検出を可能にします. このコンピュータビジョンパイプラインは 信頼性の高い心臓機能と構造測定を提供することで 臨床的実践をサポートします
科学分野:
- 心臓病科
- 人工知能
- 医療用イメージング
背景:
- 自動化された心臓画像解釈は,特にプライマリケアにおける連続評価において,臨床実務を向上させることができます.
- コンピュータビジョンの進歩は,完全に自動化されたエコーカルディオグラムの分析パイプラインの可能性を秘めています.
研究 の 目的:
- 収束神経ネットワークを用いたエコーカルジオグラムの解釈のためのスケーラブルで自動化されたパイプラインを開発し評価する.
- このパイプラインは,ビュー識別,画像セグメンテーション,構造/機能定量化,および疾患検出を目的としています.
主な方法:
- 視界識別と心室セグメンテーションのために 14,035 エコーカルジオグラムでコンボリューションニューラルネットワークモデルを訓練した.
- 断片化出力を用いて心臓の構造と機能 (エジェクション分数,縦張) を定量化した.
- ハイパルトロフィック心筋病,心臓アミロイド,肺動脈高血圧を検出するモデルを開発した.
主要な成果:
- 正確な自動視野識別 (横側長軸の96%) と室のセグメンテーション.
- 心臓構造の測定は,臨床値と一致した (例えば,体積の絶対偏差は15- 17%).
- 自動機能測定 (エジェクション分数,ストレス) は商用ソフトウェアと一致し,シリアルモニタリングの有用性を実証した.
- 疾患検出モデルは高い性能を達成した (C統計: 縮性心筋病は0. 93,心筋アミロイドは0. 87,肺動脈高血圧は0. 85)
結論:
- 自動エコーカルジオグラム解釈パイプラインは,アーカイブされた心臓画像データのスケーラブルな分析のための基盤を提供します.
- この技術は,連続的な患者の追跡と,エコーカルディオグラムの解釈の広範な臨床適用をサポートします.
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