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Updated: Oct 31, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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塩基のないニッケル触媒によるデカルボニラティブスズキ・ミヤウラ酸フッ素結合

Christian A Malapit1, James R Bour1, Conor E Brigham1

  • 1Department of Chemistry, University of Michigan, Ann Arbor, MI, USA.

Nature
|October 26, 2018
PubMed
まとめ

この研究は,外部塩基の必要性を排除し,酸性フッ素とボロン酸を効率的に結合する新しいニッケル触媒反応を導入します. この進歩は,塩基感受性基板のためのスズキ-ミヤウラクロスカップリングの範囲を拡大します.

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