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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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周期性アミンの分解的多様化

Jose B Roque1, Yusuke Kuroda1, Lucas T Göttemann1

  • 1Department of Chemistry, University of California, Berkeley, CA, USA.

Nature
|November 2, 2018
PubMed
まとめ

この研究は,飽和した窒素ヘテロサイクルの新しい分解機能化方法を導入しています. 循環性アミンの骨格的な再構成を多用途の無循環性ハロアミンに可能にし,薬剤発見に役立ちます.

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