Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

From DNA to Protein03:06

From DNA to Protein

22.4K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
22.4K
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

3.2K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
3.2K
Actin Polymerization01:42

Actin Polymerization

8.6K
Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶  nucleation, elongation, and steady-state phase.
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight...
8.6K
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

16.7K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
16.7K
DNA Helicases00:55

DNA Helicases

24.1K
DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
24.1K
DNA Packaging00:58

DNA Packaging

112.6K
Overview
112.6K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Metal-Phenolic Coatings Enable Universal Design of Spherical Nucleic Acids.

Angewandte Chemie (International ed. in English)·2026
Same author

Correction to "DNA-Mediated Cellular Delivery of Functional Enzymes".

Journal of the American Chemical Society·2026
Same author

High-χ Block Copolymer Nanoreactors for the Confined Synthesis of Size-Controlled Nanoclusters.

ACS nano·2026
Same author

Programmable Stepwise Heteroepitaxial Growth of Colloidal Crystals With Different Phases.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Simplex-based model for nanoparticle grain identification in four-dimensional scanning transmission electron microscopy data.

Journal of microscopy·2026
Same author

Investigating the <i>In Vivo</i> Performance of Tannic Acid-Modified siRNA in the Heart and Liver.

Bioconjugate chemistry·2026
Same journal

Linker Engineering toward NIR-II Metal-Organic Framework with Maximal Emission beyond 1000 nm for Inflammatory Bowel Disease Imaging.

Journal of the American Chemical Society·2026
Same journal

Observing Kinetic Selectivity in Anthracene Photodimerization through Selective Quenching by Excited States of Proximate Rare Earth Cations.

Journal of the American Chemical Society·2026
Same journal

Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers.

Journal of the American Chemical Society·2026
Same journal

Large Thermo- and Mechanosalient Actuation via Cooperative Twist Elasticity-Induced Packing Motif Conversion.

Journal of the American Chemical Society·2026
Same journal

Discovery and Biosynthesis of Lanthipeptides Featuring an Azepinoindole Scaffold by Radical <i>S</i>-Adenosylmethionine Enzyme-Catalyzed C-C Bond Formation.

Journal of the American Chemical Society·2026
Same journal

Enantiopurity-Controlled Magnetism in a Two-Dimensional Organic-Inorganic Material.

Journal of the American Chemical Society·2026
関連記事をすべて見る

関連する実験動画

Updated: Feb 2, 2026

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
09:01

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles

Published on: September 27, 2013

11.6K

タンパク質をDNAでプログラムする

Janet R McMillan, Oliver G Hayes, Jonathan P Remis

    Journal of the American Chemical Society
    |November 9, 2018
    PubMed
    まとめ
    この要約は機械生成です。

    研究者はタンパク質のポリメリゼーション経路を制御する DNAベースの戦略を開発しました この方法は,新しいタンパク質ベースの材料を作成するためのステップ成長またはチェーン成長ポリメリゼーションの正確なプログラミングを可能にします.

    さらに関連する動画

    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide
    08:51

    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide

    Published on: June 23, 2016

    11.3K
    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization
    07:28

    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

    Published on: November 27, 2015

    13.8K

    関連する実験動画

    Last Updated: Feb 2, 2026

    Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
    09:01

    Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles

    Published on: September 27, 2013

    11.6K
    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide
    08:51

    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide

    Published on: June 23, 2016

    11.3K
    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization
    07:28

    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

    Published on: November 27, 2015

    13.8K

    科学分野:

    • バイオマテリアル科学
    • 分子生物学
    • ポリマー化学

    背景:

    • タンパク質の自己組織化は 生物学的機能に不可欠です
    • タンパク質のポリメリゼーション経路の制御は困難です
    • DNAのプログラム可能性は タンパク質を直接組み立てるための 新しいアプローチを提供します

    研究 の 目的:

    • タンパク質のポリメリゼーションを制御するためのDNA媒介戦略を開発する.
    • ステップ成長とチェーン成長ポリメリゼーション経路のメカニズム的制御を達成する.
    • 制御された構造を持つタンパク質ベースのオリゴーマーとポリマーを合成する.

    主な方法:

    • 変異した緑色光タンパク質 (mGFP) -DNAモノメアの合成と特徴付け.
    • 配列特異のDNA相互作用を用いて,ポリメリゼーションエネルギーバリアをプログラムする.
    • 組み立て製品を視覚化するためのヴォルタ相板技術による冷凍電子顕微鏡

    主要な成果:

    • DNAの配列と形状を修正することによって,ステップ成長とチェーン成長のポリメリゼーション経路の両方にアクセスする能力を示した.
    • 異なるポリマー分布が観察された (段階的成長の場合,周期的/線形,鎖的成長の場合,独占的に線形).
    • チェーン成長システムの"生きている"性格を示し,チェーン拡張を可能にしました.

    結論:

    • 精密な建築制御でタンパク質ベースの材料を合成するための堅固な方法論を確立しました.
    • この研究は,DNAを用いたタンパク質組成の機械的制御の初期の例である.
    • 開発された戦略により,新しいオリゴメリックおよびポリメリックタンパク質ベースの材料の作成が可能になります.