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ユーカリのN端ルール経路のN-デグロンとしてのホルミルメチオニン

Jeong-Mok Kim1, Ok-Hee Seok1, Shinyeong Ju2,3

  • 1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, Republic of Korea.

Science (New York, N.Y.)
|November 10, 2018
PubMed
まとめ

酵母細胞リボソームは,以前は細菌に特有と考えられていたタンパク質にN-末端メチオニン (Nt-fMet) を形成することができる. このプロセスは,Gcn2キナーゼによって調節され,fMet/N-degron経路を通じて分解されるタンパク質をターゲットにします.

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