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Updated: Feb 2, 2026

Preparation of Mitochondrial Enriched Fractions for Metabolic Analysis in Drosophila
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SFXN1は,一炭素代謝に必要なミトコンドリアのセリントランスポーターである

Nora Kory1,2,3,4, Gregory A Wyant1,2,3,4, Gyan Prakash1

  • 1Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|November 17, 2018
PubMed
まとめ

シデロフレキシン1 (SFXN1) は,核酸とピュリンの合成に不可欠な,一炭素代謝に不可欠なミトコンドリアのセリントランスポーターとして特定されています. 欠乏すると,グリシンとピュリンの生成が妨げられます.

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