関連する実験動画

Updated: Feb 2, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
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Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

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ヒトのT細胞における全ゲノムCRISPRスクリーンは,免疫機能の重要な調節因子を明らかにする

Eric Shifrut1, Julia Carnevale2, Victoria Tobin1

  • 1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA.

Cell
|November 20, 2018
PubMed
まとめ

私たちはSLICEを開発しました CRISPRによる 人間のT細胞のスクリーニングです このアプローチはT細胞の反応を制御する 重要な遺伝子を特定し 癌の免疫療法と薬剤発見に 極めて重要です

キーワード:
CRISPRについてT細胞の活性化T細胞の増殖ゲノム全体のプールのスクリーニング免疫療法主要なヒトT細胞単細胞RNA-seq

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