ランタニドイオンとアミノ酸を用いた巨大なキラルモリブデンブルーホイールのステレオセレクティブ組立
Weimin Xuan1, Robert Pow1, Nancy Watfa1
1WestCHEM, School of Chemistry , The University of Glasgow , Glasgow G12 8QQ , United Kingdom.
Journal of the American Chemical Society
|November 30, 2018
まとめ
研究者らは,ランタニドとアミノ酸を使用して大きなキラルポリオキシメタレート (POM) クラスタを合成するための新しい方法を開発しました. この突破により,独特の宿主-ゲスト特性と触媒能力を持つエナチオピュア POM の作成が可能になりました.
科学分野:
- 無機化学
- 材料科学
- 超分子化学
背景:
- メタル-オクソフレームのキラリティを制御する難しさのために,本質的にキラルなポリオクソメタラート (POM) の合成は困難である.
- 既存の方法は,エナティオプアPOM形成に必要な非対称性を誘導するのにしばしば苦労します.
研究 の 目的:
- 巨大なキラルポリオキシメタレート群の ステレオ選択合成を 達成するためです
- ホスト・ゲストの化学反応と 触媒の応用について 研究する
主な方法:
- 座標ランタニドイオンをシンメトリーブレーカーとして利用した.
- キラルフレームワークの形成を誘導するためにアミノ酸リガンドを使用します.
- 円形の二重化,1H NMR,および電噴離子移動質量スペクトロメトリを用いてキラリティと安定性を特徴付けました.
主要な成果:
- 定義された Δ または Λ コンフィギュレーションを持つ巨大なキラルモリブデンブルー (MB) POMクラスター ({Mo124Ce4}) の一連の合成に成功しました.
- キラルMBフレームワークが,以前はアクセスできないキラル{Mo8}クラスタを封じ込める能力を実証した.
- トリプトファンがキヌレニンに直立的に変容することを示した.
結論:
- ステレオ選択的POM合成のためのランタニドとアミノ酸を用いたシナガティックな戦略を開発した.
- ホスト・ゲストの化学反応と 選択的触媒の 重要な可能性を示しています
- デザインの新たな道を開いた 複雑なキラル無機材料に 合わせた機能性
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