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Updated: Feb 1, 2026

Determination of High-affinity Antibody-antigen Binding Kinetics Using Four Biosensor Platforms
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Determination of High-affinity Antibody-antigen Binding Kinetics Using Four Biosensor Platforms

Published on: April 17, 2017

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細胞膜抗原への多価リンガンド結合:親和性,対価性,発現密度の相互作用を定義する

Clifford M Csizmar, Jacob R Petersburg, Thomas J Perry

    Journal of the American Chemical Society
    |December 4, 2018
    PubMed
    まとめ

    多価タンパク質ナノリングの結合親和性とバレンスを最適化することで,抗原発現が高い癌細胞を選択的に標的にし,腫瘍外毒性を最小限に抑えることができます. このアプローチはがん治療の治療精度を高めます

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