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Updated: Feb 1, 2026

A Quantitative Glycomics and Proteomics Combined Purification Strategy
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直接およびプロテオーム幅の共性阻害剤の標的部位識別のための化学タンパク質戦略

Christopher M Browne1,2, Baishan Jiang1,2, Scott B Ficarro1,2,3

  • 1Department of Cancer Biology , Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States.

Journal of the American Chemical Society
|December 7, 2018
PubMed
まとめ

新しい化学プロテオミクスの方法CITE-IDは タンパク質の共性薬物結合部位を正確にマッピングします このアプローチにより,未十分に研究されたPKN3キナーゼを含む新薬開発標的が特定され,新しい選択性阻害剤が開発されました.

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