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Updated: Feb 1, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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メソトレキサート化学療法は,化学療法による認知障害の根底にある持続的なトライグリアルディス調節を誘導する

Erin M Gibson1, Surya Nagaraja1, Alfonso Ocampo1

  • 1Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA 94305, USA.

Cell
|December 12, 2018
PubMed
まとめ

化学療法はオリゴデンドロサイト前駆細胞 (OPCs) と白質を破壊することで,長期的な神経学的欠陥を引き起こす. 炎症性マイクログリアをターゲットにすることで,化学療法による認知障害を防ぐことができます.

キーワード:
OPC についてアストロサイトケモブレイン化学療法化学療法による認知障害マイクログリアミエリンオリゴデンドロサイト

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