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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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二機能アミノ反応剤を用いたステレオ特異アルケンのアジリディネーション: アザ・プリレザエフ反応

Joshua J Farndon1, Tom A Young1, John F Bower1

  • 1School of Chemistry , University of Bristol , Bristol BS8 1TS , United Kingdom.

Journal of the American Chemical Society
|December 14, 2018
PubMed
まとめ

O-T活性化N-Bocヒドロキシラミンのトリフロアセチン酸 (TFA) 脱保護は,分子内アジリジネーションを誘導する. この反応は,分子間応用の可能性のあるステレオ特異なメカニズムを通じて,複雑なN-ヘテロサイクルリングを効率的に形成します.

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