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Updated: Feb 1, 2026

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

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フラビウイルスと宿主タンパク質の相互作用の比較マッピングは,デング熱とジカウイルスの病原性を明らかにする

Priya S Shah1, Nichole Link2, Gwendolyn M Jang3

  • 1Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA; The J. David Gladstone Institutes, San Francisco, CA, USA.

Cell
|December 15, 2018
PubMed
まとめ

デング熱やジカのような 蚊媒介のフラビウイルスは タンパク質の相互作用によって 細胞を乗っ取ります SEC61を標的にすると ウイルスの複製が妨げられ ジーカタンパク質の相互作用が 微頭症の説明となり 新しい治療法が生まれます

キーワード:
ANKLE2 についてドロソフィラPAF1Cセクション61ジカウイルスデング熱 ウイルスエンドプラズマの網膜フラビウイルスインターフェロン刺激遺伝子マイクロケファリープロテオミクス

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