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Updated: Jan 31, 2026

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
07:40

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Published on: August 30, 2019

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ハイドロキシクロロクインによって制限された急性リウマチ熱におけるIL-1β-GM-CSF軸の調節不全

Man Lyang Kim1,2, William J Martin1,2, Gabriela Minigo3

  • 1Divisions of Inflammation (M.L.K., W.J.M., J.L.K., I.P.W.), Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Circulation
|December 21, 2018
PubMed
まとめ

研究者らは,急性リウマチ熱 (ARF) に関するインターレウキン-1βと粒細胞マクロファージコロニー刺激因子 (GM-CSF) を含む重要なサイトカイン経路を特定した. ヒドロキシクロロキンはこの経路を効果的に抑制し,リウマチ性心疾患の予防の可能性を示唆した.

キーワード:
GM-CSF についてIL-1β自己免疫性ハイドロキシクロロクインリウマチ性心臓病

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