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Updated: Jan 31, 2026

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p53はメバロナート経路を抑制し,腫瘍抑制を媒介する

Sung-Hwan Moon1, Chun-Hao Huang2, Shauna L Houlihan3

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Cell
|December 25, 2018
PubMed
まとめ

腫瘍抑制剤p53は メバロナート経路を遮断することで 肝がんを抑制します この経路はコレステロールの生物合成に不可欠であり,SREBP-2の活性化によって調節されます.

キーワード:
ABCA1 についてSREBP-2 について癌の代謝メバロナート経路p53 について腫瘍抑制

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