静止型中年における2年間の高強度運動訓練後の左心房の電気機械的改造
David A McNamara1,2, Norman Aiad1,2, Erin Howden2
1Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (D.A.M., N.A., M.S.L., S.S., B.D.L.).
Circulation
|December 28, 2018
まとめ
高強度運動は,座っている成人の左心房 (LA) を24ヶ月で大きく膨らませた. このメカニカルな改造は電気的な変化なしに行われ 運動による心臓適応の 明確な値を示唆しています
科学分野:
- 心臓病科
- 運動 生理学
- 心臓の改造
背景:
- 適度な運動は心房細動 (AF) のリスクを軽減します.
- スポーツ選手の激しいトレーニングは AFの発生率の増加と関連しています.
- 長期にわたる高強度運動が非スポーツ選手の心臓の改造に与える影響は不明である.
研究 の 目的:
- 左心房 (LA) の機械的および電気的改造に 24 ヶ月の高強度運動の影響を調査する.
- 構造的な運動プログラムを受けている中年の座っている成人の変化を評価するために
主な方法:
- 61人の定着型成人 (53年±5年) を対象としたランダム化比較試験.
- 10ヶ月の高強度運動と14ヶ月の維持運動と ストレッチ/バランスコントロールの比較です
- 評価には,LA/LVの体積の3Dエコーカルディオグラフィーと,電気的パラメータのエレクトロカルディオグラフィーが含まれていました.
主要な成果:
- 高強度運動は10ヶ月後に LAとLVの量に比例した増加をもたらしました.
- LAの量は24ヶ月間にわたって大幅に増加し (ベースラインと比較して55%の増加),LVの変化を上回りました.
- グループ間では,心房の電気特性やAF検出の有意な変化は見られなかった.
結論:
- 24ヶ月の高強度運動は 左心房のメカニカルリモデリングを誘発し 左心房の変化に比例しない.
- 運動のメカニカルと電気的適応には 異なる値が存在します
- この発見は,高強度運動と心房細動のリスクを関連付けている可能性のあるメカニズムを示しています.
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