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Updated: Jan 31, 2026

Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice
07:36

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Published on: September 26, 2018

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MALAT1 長い非コーディングRNAの血液形成欠乏症 動脈硬化とプラーク炎症を促進する

Sebastian Cremer1,2, Katharina M Michalik1, Ariane Fischer1

  • 1Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Goethe University, Frankfurt, Germany (S.C., K.M.M., A.F., L.P., N.J., R.A.B., M.M.-R., D.J., S.U., S.D.).

Circulation
|December 28, 2018
PubMed
まとめ

長い非コーディングRNAMALAT1のレベルが低下すると,マウスとヒトの炎症性細胞の蓄積が増加し,動脈硬化症が悪化する. 低MALAT1は動脈硬化症の予後が悪いことを示している.

キーワード:
RNA について動脈硬化症炎症白血球

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