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Updated: Jan 31, 2026

A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9
08:14

A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9

Published on: August 28, 2018

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脂質タンパク質 (a),PCSK9阻害,および心血管リスク

Michelle L O'Donoghue1, Sergio Fazio2, Robert P Giugliano1

  • 1TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (M.L.O., R.P.G., E.K., K.A.I., M.S.S.).

Circulation
|December 28, 2018
PubMed
まとめ

脂質タンパク質のレベルが上がると 心血管疾患のリスクが増加します エボロキュマブはPCSK9阻害剤で,Lp (a) を効果的に低下させ,発症時のLp (a) が上昇した患者の冠動脈により大きな効果をもたらします.

キーワード:
動脈硬化症臨床試験脂質タンパク質 (a)

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