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エンパグリフロジンは,EMPA- REG OUTCOME試験における心血管リスクの全スペクトルにおいて,心不全による死亡率と入院率を減少させた.

  • 0St Michael's Hospital, Division of Cardiology, University of Toronto, Canada (D.F.).
Circulation +

|

2018年12月28日

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Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...