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Updated: Jan 31, 2026

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
08:04

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling

Published on: October 8, 2019

9.1K

小さな螺旋状の束は,DNAテンプレートのシーケンス固有の認識を向上させる2つのヌクレオチドを結合することによって,プライマー合成を準備する

Julien Boudet1, Jean-Christophe Devillier2, Thomas Wiegand3

  • 1Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zürich, 8093 Zürich, Switzerland.

Cell
|January 1, 2019
PubMed
まとめ

アーカイアル・プライマースはヘリックスバンドルドメイン (HBD) を用いてDNAテンプレートを結合する. 核酸結合はアロステリック変化を引き起こし,プライマー合成のための配列特異のDNA結合を可能にします.

キーワード:
DNA複製NMR についてアルカイウカリオット・プライマースディヌクレオチド合成強化された特異性ヘリックスバンドル領域ハイブリッド構造タンパク質-DNA複合体シンジェスティック・バインディングテンプレート・バイディング

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