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Updated: Jan 31, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
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DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

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RUNX転写因子を標的にするDNAアルキル化PIポリアミドの分子特性

Rina Maeda1, Shinsuke Sato2, Shunsuke Obata2

  • 1Graduate School of Advanced Integrated Studies in Human Survivability , Kyoto University , Sakyo, Kyoto 606-8306 , Japan.

Journal of the American Chemical Society
|January 3, 2019
PubMed
まとめ

癌の増殖に関与するRUNXタンパク質を抑制する 新しいDNAアルキル化薬であるコンジュガート1を開発しました 改変によりコンジュガート2が得られ,潜在的ながん治療薬に対するDNA結合と選択性が改善された.

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Overview
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