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Updated: Jan 30, 2026

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors

Published on: June 8, 2022

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シグナリングカンナビノイド受容体1-Gタンパク質複合体の構造

Kaavya Krishna Kumar1, Moran Shalev-Benami2, Michael J Robertson2

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.

Cell
|January 15, 2019
PubMed
まとめ

研究者は,MDMB-Fubinaca (FUB) に結合するカンナビノイド受容体1 (CB1) の構造を明らかにした. この構造はFUBがCB1-Giのシグナル伝達をどのように活性化するかを明らかにし 神経学的障害の治療法を理解するのに不可欠です

キーワード:
CB1 についてフビナカG ((i) についてGPCR についてカナビノイド受容体クリオ・エム合成カンナビノイド

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