Jove
Visualize
お問い合わせ

関連する概念動画

RNA Splicing01:32

RNA Splicing

60.6K
Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
60.6K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

9.9K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.9K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

3.6K
3.6K
Alternative RNA Splicing02:18

Alternative RNA Splicing

25.1K
Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
25.1K
Alternative RNA Splicing02:18

Alternative RNA Splicing

5.1K
5.1K
Nursing Code of Ethics01:29

Nursing Code of Ethics

4.5K
The Nursing Code of Ethics sets the ethical benchmark for the profession, and guides nurses in ethical analysis and decision making at the societal, organizational, and clinical levels. The code encompasses showing compassion and respect for the patient, their families, and communities in all circumstances while committing to providing patient-centered care. In addition, the code states that nurses must advocate for the patient by defending a cause or recommendation to protect their rights,...
4.5K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Onconeural antigen NOVA1 dysregulates RNA alternative splicing in breast cancer.

RNA (New York, N.Y.)·2026
Same author

Global research landscape in pharmacotherapy for autism spectrum disorder core symptoms: a bibliometric study.

Translational pediatrics·2026
Same author

Searching for potential biosignatures in impact-induced hydrothermal systems on Mars.

Science bulletin·2026
Same author

Exon inclusion signatures enable accurate estimation of splicing factor activity.

Nature communications·2026
Same author

Single-cell RNA sequencing of adenoid cystic carcinoma of the breast reveals cellular heterogeneity and tumor microenvironment features.

BMC medical genomics·2026
Same author

A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability.

Nature communications·2026
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
関連記事をすべて見る
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する実験動画

Updated: Jan 30, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
08:35

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

6.4K

スプライシング コード は 深い

Suying Bao1, Daniel F Moakley1, Chaolin Zhang1

  • 1Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA.

Cell
|January 26, 2019
PubMed
まとめ
この要約は機械生成です。

ゲノム配列の文脈はRNAのスプライシングに大きく影響し,トランスクリプトームの多様性を生み出します. これらの発見は,遺伝子発現と細胞機能の調節における DNA 配列の重要な役割を強調しています.

さらに関連する動画

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
10:06

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

9.4K
Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
11:48

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

13.4K

関連する実験動画

Last Updated: Jan 30, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
08:35

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

6.4K
Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
10:06

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

9.4K
Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
11:48

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

13.4K

科学分野:

  • 分子生物学
  • ゲノミクス
  • トランスクリプトミクス

背景:

  • RNA スプライシングは,トランスクリプトームの多様性を生み出す重要なポストトランスクリプションの修正です.
  • ゲノム配列の文脈がRNAスプライシングに及ぼす影響は,活発な調査分野である.

研究 の 目的:

  • RNA スプライシングにおけるゲノム配列文脈の役割を明らかにする.
  • 配列の文脈がトランスクリプトームの多様性にどのように貢献するのかを理解する.

主な方法:

  • ゲノム配列の分析とスプライシングパターンとの相関
  • 異なるゲノムに関する比較研究

主要な成果:

  • ゲノム配列の文脈はRNAスプライシングの結果の重要な決定因子です.
  • ゲノム内の特定の配列要素は,代替スプライシングイベントに影響を与えます.
  • この文脈は,トランスクリプトームの多様性の完全なスペクトルを生成するために不可欠です.

結論:

  • ゲノム配列の文脈は RNA スプライシングにおいて根本的な役割を果たします
  • スプライシングの配列ベースの調節を理解することは,遺伝子発現と細胞機能を理解するために不可欠です.