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Updated: Jan 30, 2026

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
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異卵性変異は,酵母型がんの進化における遺伝的不安定性を引き起こします

Miguel C Coelho1,2,3, Ricardo M Pinto4,5, Andrew W Murray6,7

  • 1FAS Center for Systems Biology, Harvard University, Cambridge, MA, USA. mcc150@gmail.com.

Nature
|February 1, 2019
PubMed
まとめ

単一の遺伝子変異は酵母に 遺伝的不安定性をもたらし 進化を加速し 癌に 寄与する可能性があります この研究は,ヒトの病気の研究に意味を持つ,不安定性に関連した新しい遺伝子標的を特定しました.

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