筋肉トレーニングにインスパイアされた機械反応性自己成長ヒドロゲル

Takahiro Matsuda¹, Runa Kawakami¹, Ryo Namba¹

¹Graduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo 001-0021, Japan.

Science (New York, N.Y.)

|February 2, 2019

まとめ

研究者達は繰り返し機械的なストレスをかけることで強化される自己増殖ポリマー材料を開発しました機械化学のこの突破は材料を自律的に修復し適応させ生物の組織を模倣して高度な応用を可能にします

科学分野:

ポリマー科学
材料科学
バイオ材料工学

背景:

生きた組織は,メカニカルな刺激に反応して代謝プロセスを通して自律的に成長し,再構築します
従来の合成材料は形成後に成長したり構造を再構築する能力がありません
合成材料と生物学的適応性の間のギャップを埋めることは,材料科学の重要な課題です.

研究の目的:

機械的ストレスに反応できる新種の自己増殖ポリマー材料の開発
破壊-再構築メカニズムで自律的に成長し強化できる素材を設計する
適応性のある合成材料を作るための機械化学変換の可能性を探求する.

主な方法:

頑丈な二重ネットワークの水素ガスを使用し,連続したモノマー供給を行います.
機械的ストレスと物質の成長を結びつけるための機械化学変換戦略の実施.
自発的に成長するヒドロゲルに局所的な機能を与えるために機械的なスタンピングを使用します.

主要な成果:

開発された水素ゲルは,繰り返し機械的な負荷にさらされると,自律的な自己成長を示した.
材料は,継続的な構造破壊とストレス下での再構築プロセスにより,著しく強化されました.
機械的なスタンピングにより特定の場所での材料の機能の調整が成功しました

結論:

提案された戦略は,機械的なストレス下で適応し,強化する自己成長するポリマー材料の作成を可能にします.
この機械化学的アプローチは合成材料で生体組織の再構築を模倣する道を示しています
潜在的応用には,高度なソフトロボット,自己治癒装置,インテリジェント・マテリアル・システムなどがあります.

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