ENGAGES のランダム化臨床試験
PubMedで要約を見る
まとめ
この要約は機械生成です。大手術を受けた高齢者の間では,脳波 (EEG) 誘導による麻酔は術後の妄想を軽減しなかった. この研究は,現在のEEGガイドラインが,この患者集団における妄想を予防するのに有益でないことを示唆しています.
科学分野
- 麻酔科
- 神経科学
- 高齢者医療
背景
- 術内電気脳波 (EEG) の波形抑制は,過度の全身麻酔と術後の妄想と関連しています.
- 手術後の妄想は,大きな手術を受ける高齢者の大きな懸念です.
研究 の 目的
- 電気脳波 (EEG) 誘導による麻酔薬の投与が老年手術患者における術後の妄想の発生率を減少させるかどうかを判断する.
主な方法
- 60歳以上の大人の1232人を対象としたランダム化臨床試験です.
- 患者はランダムに選んでEEGによる麻酔か通常の麻酔治療を受けた.
- 主な評価項目は,手術後1日から5日間の妄想の発生率でした.
主要な成果
- 妄想は,EEG誘導群の26. 0%で,通常の治療群の23. 0%で発生した (P=.
- EEG誘導による麻酔は,麻酔濃度が低く,EEG抑制が少なくなった.
- グループ間の低血圧,手術中の意識,手術後の吐き気および嘔吐の有意な違いは観察されなかった.
結論
- 大手術を受けた高齢者において,EEGによる麻酔投与は,術後の妄想の発生率を減少させなかった.
- この集団における術後の妄想を予防するために,EEGによる麻酔投与の使用は支持されません.
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