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アジドグループによる支援により,非ヘム鉄ヒドロキシレースの再利用により,触媒性ニトリル装置が可能になる

Madison Davidson1, Meredith McNamee1, Ruixi Fan2

  • 1Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.

Journal of the American Chemical Society
|February 14, 2019
PubMed
まとめ

鉄酵素は,アジド群を導入することによって,ヒドロキシルではなくニトリルを形成するように再誘導することができる. この発見により,非ヘム鉄と2オキシグルタレット依存酵素の触媒能力が拡大した.

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