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Updated: Jan 28, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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PqqBのヒドロキシラーゼ活性に関する発見は,ピロロキノリンキノン生物合成経路における欠けているリンクを提供する

Eric M Koehn1, John A Latham1, Tara Armand1

  • 1Department of Chemistry and California Institute for Quantitative Biosciences , University of California-Berkeley , Berkeley , California 94720-3220 , United States.

Journal of the American Chemical Society
|February 28, 2019
PubMed
まとめ

研究者はPQQ生物合成酵素PqqBの機能を特定しました. この鉄に依存するヒドロキシラーゼは酸素の挿入を触媒化し,ピロロキノリンキノン (PQQ) 協因子生物合成の理解を完了します.

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