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Updated: Jan 28, 2026

Methods for Culturing Human Femur Tissue Explants to Study Breast Cancer Cell Colonization of the Metastatic Niche
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乳がん 細胞 は 周囲 の ピルバート に 依存 し て 転移 する 場所 を 形成 する

Ilaria Elia1,2, Matteo Rossi1,2, Steve Stegen3

  • 1Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.

Nature
|March 1, 2019
PubMed
まとめ

乳がん細胞は肺転移で細胞外マトリックスを再構成するために 栄養素のピルベートを使用します ピルバートは転移に欠かせない コラーゲンの水酸化を促し このプロセスを阻害することで 腫瘍の広がりを遅らせます

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