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Updated: Jan 28, 2026

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets
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全ゲノム解析により,NR4A1がT細胞機能障害の主要な媒介者であると確認された

Xindong Liu1, Yun Wang2, Huiping Lu3

  • 1Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China. xindongliu@hotmail.com.

Nature
|March 1, 2019
PubMed
まとめ

転写因子NR4A1はT細胞の機能障害と耐性を誘発する. NR4A1ががん免疫治療の標的となる可能性を示唆する.

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