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Updated: Jan 28, 2026

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq
06:22

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq

Published on: August 25, 2020

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単細胞RNA-Seqは,病気の進行と免疫に関連するAMLの階層を明らかにする

Peter van Galen1, Volker Hovestadt1, Marc H Wadsworth Ii2

  • 1Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Ludwig Center at Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Cell
|March 5, 2019
PubMed
まとめ

この研究では,急性骨髄性白血病 (AML) の様々な細胞型が特定され,遺伝子の変異が特定の細胞状態と結びついていることが明らかになりました. 発見はAMLの進行や 精密医療の潜在的標的についての洞察を提供します.

キーワード:
急性骨髄性白血病癌の遺伝学遺伝子型決定免責権白血病の幹細胞単細胞RNAシーケンシング

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