関連する実験動画

Updated: Jan 28, 2026

High-throughput Measurement of Plasma Membrane Resealing Efficiency in Mammalian Cells
10:07

High-throughput Measurement of Plasma Membrane Resealing Efficiency in Mammalian Cells

Published on: January 7, 2019

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フォスフォノシチドの相互作用 プラズマ膜にcGASを配置し,自己DNAとウイルスDNAを効果的に区別する

Katherine C Barnett1, Julia M Coronas-Serna2, Wen Zhou3

  • 1Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

Cell
|March 5, 2019
PubMed
まとめ

細胞塩基DNAセンサ cGASは細胞塩基ではなく,血に局所する. フォスフォノシチド結合ドメインによるこの位置付けは,免疫反応の間に自己と非自己を区別するために重要である.

キーワード:
スティングcGAS について生まれつきの免疫インターフェロン地元化マクロファージフォスフォノシチド

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