分子流とアングストロームスケールチャネルにおける電圧制御
T Mouterde1, A Keerthi2,3, A R Poggioli1
1Laboratoire de Physique de l'Ecole normale supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université Paris-Diderot, Sorbonne Paris Cité, Paris, France.
Nature
|March 8, 2019
まとめ
研究者はナノスケールチャネルで トランジスタのような効果を発見し 電気場が水とイオンの流れを劇的に制御します 石墨と六角性酸塩で観察されるこの電動水力学ゲーティングは,分子輸送を管理するための新しい方法を提供します.
科学分野:
- 物理学
- 材料科学
- ナノテクノロジー
背景:
- ナノスケールの流体装置は 独特の水とイオン輸送現象を明らかにします
- 2次元の材料はアングストロームスケールの精度で人工チャネルを可能にし,連続輸送モデルに挑戦します.
- 分子閉じ込めは 壁の相互作用により 水の性質とイオン運動を変化させます
研究 の 目的:
- 水とイオンの結合輸送を 分子サイズのスリートのようなチャネルで調査する
- 閉じ込められた状態でのイオン流体輸送の電気水力学的効果を探求する.
- 輸送現象における物質依存の違いを理解する.
主な方法:
- 圧力と電場によって駆動されるイオン流体輸送の測定.
- グラファイトと六角形の酸塩でできた 分子型のスリート型のチャネルを使用します
- 摩擦相互作用を分析するために修正された連続体フレームワークを適用します.
主要な成果:
- トランジスタのような電気水力学的効果が観察され,小さな偏差で圧力駆動によるイオン輸送 (20倍まで) が著しく増加した.
- このゲーティング効果は,グラファイトと六角性酸塩チャネルの両方で存在しましたが,材料に依存する明確な変化がありました.
- この研究では,さまざまな電気条件下での流動性を定量化しました.
結論:
- 分子スケールの閉じ込めは 流体輸送の高度な非線形ゲートを可能にします
- 観測された電気水力学的効果は,分子とイオン輸送を制御するための新しい戦略を提供します.
- 機械感受性チャネルのような生物学的システムにおける電気機械的結合を明らかにすることができる.
さらに関連する動画
11:42Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies
Published on: January 22, 2015
19.9K
08:25Voltage and Calcium Dual Channel Optical Mapping of Cultured HL-1 Atrial Myocyte Monolayer
Published on: March 23, 2015
10.8K
関連する概念動画
Voltage-gated Ion Channels
10.7K
Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several types of...
Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several types of...
10.7K
Generator Voltage Control
652
Generator voltage control is crucial for maintaining the stable operation of synchronous generators and wind turbines. In older models, a DC generator driven by the rotor delivers DC power to the rotor's field winding, and the power is transferred through slip rings and brushes. In the latest models, static or brushless exciters are used. Static exciters rectify AC power from the generator terminals and then transfer the DC power directly to the rotor. Brushless exciters, on the other hand, use...
652
Stream Function
2.1K
In two-dimensional incompressible fluid flow, the continuity equation is essential for ensuring mass conservation, meaning that any change in fluid entering or exiting a region is balanced by a corresponding change elsewhere. For incompressible flow, where density remains constant, this requirement simplifies to the condition that the divergence of the velocity field must be zero. Mathematically, this is expressed as,
2.1K
Ion Channels
91.4K
The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.4K
Voltage
4.1K
The movement of electrons in a conductor requires some form of energy or work, usually provided by an external force, like a battery. This force is called the electromotive force or voltage. The voltage between two points, referred to as points "a" and "b," in an electric circuit is the energy (or work) needed to move a unit charge from point "a" to point "b," and this relationship is expressed mathematically as
4.1K
pH Scale
79.4K
Hydronium and hydroxide ions are present both in pure water and in all aqueous solutions, and their concentrations are inversely proportional as determined by the ion product of water (Kw). The concentrations of these ions in a solution are often critical determinants of the solution’s properties and the chemical behaviors of its other solutes. Two different solutions can differ in their hydronium or hydroxide ion concentrations by a million, billion, or even trillion times. A common means of...
79.4K
