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Updated: Jan 28, 2026

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cGAS経路の主要な機能は,STINGトラフィックによる自己消化誘導である

Xiang Gui1, Hui Yang1, Tuo Li1

  • 1Department of Molecular Biology, Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Nature
|March 8, 2019
PubMed
まとめ

インターフェロン遺伝子 (STING) のサイクルGMP- AMP (cGAMP) 合成酵素 (cGAS) 刺激経路は,細胞の浄化プロセスであるオートファギーを活性化します. このオートファギーの誘導は細胞塩基DNAとウイルスの除去に不可欠です.

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