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Updated: Jan 28, 2026

Fluorescence-based Neuraminidase Inhibition Assay to Assess the Susceptibility of Influenza Viruses to The Neuraminidase Inhibitor Class of Antivirals
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Fluorescence-based Neuraminidase Inhibition Assay to Assess the Susceptibility of Influenza Viruses to The Neuraminidase Inhibitor Class of Antivirals

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インフルエンザウイルスの小分子融合阻害剤は,マウスの口服で活性化しています

Maria J P van Dongen1,2, Rameshwar U Kadam3, Jarek Juraszek4

  • 1Janssen Prevention Center, Janssen Pharmaceutical Companies of Johnson & Johnson, Archimedesweg 6, Leiden, Netherlands. mvandon@its.jnj.com wilson@scripps.edu.

Science (New York, N.Y.)
|March 9, 2019
PubMed
まとめ

研究者らは,インフルエンザのヘマグルチニン (HA) 幹を標的とした,広範に中和する抗体 (bnAbs) を模倣する小分子を開発しました. 経口投与されたこれらの化合物は,インフルエンザAウイルスを中和し,感染から保護し,潜在的な新しい治療戦略を提供します.

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