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Updated: Jan 28, 2026

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Akt媒介によるNADキナーゼのリン酸化によるNADP+合成の直接刺激

Gerta Hoxhaj1, Issam Ben-Sahra2, Sophie E Lockwood1

  • 1Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Science (New York, N.Y.)
|March 9, 2019
PubMed
まとめ

成長因子シグナリングは,Aktのリン酸化によってNADキナーゼ (NADK) を活性化し,代謝に不可欠なNADP+の産生を促進します. この調節は,還元性細胞プロセスのためのNADPHの可用性を高めます.

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